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CX3CR1, Biotin, clone: 2A9-1, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-6099-80

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15310000

  • £87.94 / 25µg


Estimated Shipment date
from Supplier 25-05-2018
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Description

Description

Description: This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B.Applications Reported: This 2A9-1 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 2A9-1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CX3CR1
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P49238
CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
2A9-1
Biotin
CX3CR1
Conjugated
CX3CR1
IgG2b, kappa
25μg
Store at 2-8°C. Do not freeze.
Primary
1524
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