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Tocris Bioscience™ CP 376395 hydrochloride

Potent and selective CRF1 antagonist; binds at an allosteric site

POA

Specifications

Purity >99%
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Description

Description

Potent and selective CRF1 receptor antagonist (Ki values are 12 and >10000 nM for CRF1 and CRF2 receptors respectively). Attenuates CRF-induced activation of the HPA axis in vivo following i.v. administration. Orally active.
Specifications

Specifications

>99%
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