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Thermo Scientific™ COX2, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ COX2, Rabbit Polyclonal Antibody.

Brand:  Thermo Scientific™ RB-9072-R1

Code : LD

Additional Details : Weight : 1.00000kg

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Product Code. 12623457

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance


Description

Description

COX2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate-early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, and Rat. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide corresponding to C-terminus of rat COX2

Molecular Weight: 70 kDa

Positive Control: HT29 cells, Lung and colon CA

Cellular Localization: Cytoplasmic and membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation
Specifications

Specifications

COX2
Polyclonal
Ready-to-use for IHC (UVLP)
Rabbit
IgG
IVD
Primary
Polyclonal
ImmunoprecipitationþWestern Blot
Unconjugated
Prediluted
Synthetic peptide corresponding to c-terminus of rat COX2
1mL
Enzyme
Primary
HumanþMurine
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