Thermo Scientific™ COX2, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ COX2, Rabbit Polyclonal Antibody.

Overview
Brand: Thermo Scientific™

Manufacturer Part Number: RB-9072-R1

1 ML POLYCLONAL ANTIBODY, ANTI-COX2, HOST RABBIT,isotype IgG, species reactivity human (Hu), mouse

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 12623457

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Description and Specification

Specification

Antigen COX2
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Prediluted
Formulation Ready-to-use for IHC (UVLP)
Host Species Rabbit
Immunogen Synthetic peptide corresponding to c-terminus of rat COX2
Isotype IgG
Quantity 1mL
Regulatory Status IVD
Research Discipline Enzyme
Type Primary

COX2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate-early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, and Rat. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide corresponding to C-terminus of rat COX2

Molecular Weight: 70 kDa

Positive Control: HT29 cells, Lung and colon CA

Cellular Localization: Cytoplasmic and membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation