COX IV Mouse anti-Human, eFluor 570, Clone: IB52C31H10, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 41-9775-80

25UG Anti-Human COX IV eFluor 570

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15508976

Quantity Price
1 £ 110.9 / 25µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Antigen COX IV
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Clone IB52C31H10
Concentration 0.2mg/mL
Conjugate eFluor 570
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Cytochrome c oxidase, Subunit IV, Complex IV
Host Species Mouse
Isotype IgG1
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The IB52C31H10 monoclonal antibody recognizes human COX IV. COX IV, also known as cytochrome c oxidase (COX) or Complex IV, is the terminal complex of the electron transport chain. COX IV is encoded by nuclear DNA and localized to the inner mitochondrial membrane. COX IV functions in energy metabolism and shuttles electrons from cytochrome c to oxygen. Dysfunction in COX IV is associated with increased production of reactive oxygen species and cellular toxicity. Genetic defects in COX IV results in severe, often fatal metabolic disorders that primarily affect tissues with high energy demands such as heart, brain, and muscle.