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COX4, Alexa Fluor 488, clone: IB52C31H10, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-9775-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15530297

  • £83.79 / 25µg


Estimated Shipment date
from Supplier 22-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The IB52C31H10 monoclonal antibody recognizes human COX IV. COX IV, also known as cytochrome c oxidase (COX) or Complex IV, is the terminal complex of the electron transport chain. COX IV is encoded by nuclear DNA and localized to the inner mitochondrial membrane. COX IV functions in energy metabolism and shuttles electrons from cytochrome c to oxygen. Dysfunction in COX IV is associated with increased production of reactive oxygen species and cellular toxicity. Genetic defects in COX IV results in severe, often fatal metabolic disorders that primarily affect tissues with high energy demands such as heart, brain, and muscle.Applications Reported: This IB52C31H10 antibody has been reported for use in microscopy, immunohistochemical staining, immunocytochemistry, immunohistochemical staining of frozen tissue sections, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This IB52C31H10 antibody has been tested by immunocytochemistry of MeOH-fixed human cells and can be used at less than or equal to 10μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

COX IV
IB52C31H10
Alexa Fluor 488
Conjugated
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Microscopy
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Cytochrome c oxidase, Subunit IV, Complex IV
IgG1
RUO
Primary
Human
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