Connexin 43 Mouse anti-Mouse, Clone: Connexin43 (1A), eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-4759-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg

Disclaimers: For Research Use Only.

Product Code. 15577446

Quantity Price
1 £ 155.16 / 100µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification


Applications Immunocytochemistry
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Species Reactivity Human, Mouse, Rat
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Host Species Mouse
Quantity 100μg
Clone Connexin43 (1A)
Format Purified
Primary or Secondary Primary
Antigen Connexin 43
Regulatory Status RUO

The Connexin43 monoclonal antibody recognizes mouse Connexin 43. Connexins are a family of integral membrane proteins that form gap junction channels, which function to facilitate direct cell-cell communication. Gap junctions are comprised of two hemichannels, or connexons, which are made up of six connexin proteins. Over 20 connexin proteins have been identified and each combine to form either homomeric or heteromeric channels with different functional properties. Connexin 43 is expressed in many tissues, including the central nervous system, heart, and bone. Connexin 43 is the most abundant connexin found in the myocardium and is also the primary connexin expressed in astrocytes. Mutations in connexin 43 are associated with ocluodentodigital dysplasia, a rare developmental disorder characterized by craniofacial and limb abnormalities. Connexin 43 may also be a promising therapeutic target in the treatment of malignant melanomas and mammary gland tumors.

The monoclonal antibody Connexin43 also recognizes human and rat connexin 43.