missing translation for 'onlineSavingsMsg'
Learn More

Connexin 43 Mouse anti-Mouse, Biotin, Clone: Connexin43 (1A), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-4759-80

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15567336

  • £61.70 / 25µg


Estimated Shipment date
from Supplier 25-09-2017
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The Connexin43 monoclonal antibody recognizes mouse Connexin 43. Connexins are a family of integral membrane proteins that form gap junction channels, which function to facilitate direct cell-cell communication. Gap junctions are comprised of two hemichannels, or connexons, which are made up of six connexin proteins. Over 20 connexin proteins have been identified and each combine to form either homomeric or heteromeric channels with different functional properties. Connexin 43 is expressed in many tissues, including the central nervous system, heart, and bone. Connexin 43 is the most abundant connexin found in the myocardium and is also the primary connexin expressed in astrocytes. Mutations in connexin 43 are associated with ocluodentodigital dysplasia, a rare developmental disorder characterized by craniofacial and limb abnormalities. Connexin 43 may also be a promising therapeutic target in the treatment of malignant melanomas and mammary gland tumors.

The monoclonal antibody Connexin43 also recognizes human and rat connexin 43.
Specifications

Specifications

Connexin 43
Connexin43 (1A)
Biotin
Conjugated
IgG1
RUO
Primary
Rat
Immunohistochemistry (Frozen)
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C. Do not freeze.
Monoclonal