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Connexin 32 Mouse, Biotin, Clone: Connexin32 (2A), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-9759-82

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15537376

  • £158.36 / 100µg


Estimated Shipment date
from Supplier 31-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The Connexin32 monoclonal antibody recognizes human, mouse, rat, and chicken Connexin 32. Connexins are a family of integral membrane proteins that form gap junction channels, which function to facilitate direct cell-cell communication. Gap junctions are comprised of two hemichannels, or connexons, which are made up of six connexin proteins. Over 20 connexin proteins have been identified and each combine to form either homomeric or heteromeric channels with different functional properties. Connexin 32 is expressed by myelin, neurons, oligodendrocytes, and hepatocytes, and plays a role in the development of ovarian follicles. Connexin 32 expression also plays a role in disease progression in chronic multiple sclerosis and experimental autoimmune encephalomyelitis. Mutations in the Connexin 32 gene, GJB1, result in a form of Charcot-Marie-Tooth disease which is characterized by peripheral nerve dysfunction.
Description & Specifications

Specifications

Connexin 32
Connexin32 (2A)
Biotin
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze.
Monoclonal
Western Blot
0.5mg/mL
Conjugated
Gap junction protein beta-1
IgG1
RUO
Primary
Rat