Connexin 32 Mouse, Biotin, Clone: Connexin32 (2A), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-9759-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15537376

Quantity Price
1 £ 158.36 / 100µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Western Blotting
Concentration 0.5mg/mL
Format Conjugated
Conjugate Biotin
Quantity 100μg
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone Connexin32 (2A)
Antigen Connexin 32
Isotype IgG1
Host Species Mouse
Regulatory Status RUO
Species Reactivity Chicken, Human, Mouse, Rat
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze.
Gene Alias Gap junction protein beta-1

The Connexin32 monoclonal antibody recognizes human, mouse, rat, and chicken Connexin 32. Connexins are a family of integral membrane proteins that form gap junction channels, which function to facilitate direct cell-cell communication. Gap junctions are comprised of two hemichannels, or connexons, which are made up of six connexin proteins. Over 20 connexin proteins have been identified and each combine to form either homomeric or heteromeric channels with different functional properties. Connexin 32 is expressed by myelin, neurons, oligodendrocytes, and hepatocytes, and plays a role in the development of ovarian follicles. Connexin 32 expression also plays a role in disease progression in chronic multiple sclerosis and experimental autoimmune encephalomyelitis. Mutations in the Connexin 32 gene, GJB1, result in a form of Charcot-Marie-Tooth disease which is characterized by peripheral nerve dysfunction.