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Co 101244 hydrochloride, Tocris Bioscience™

GluN2B-selective NMDA antagonist

Brand:  Tocris (Bio-Techne) 245650

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

 View more versions of this product

Product Code. 13441244

  • £414.72 / 50mg

Estimated Shipment
27-06-2019

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Description

Description

Novel, potent and selective antagonist of GluN2B (formally NR2B)-containing NMDA receptors (IC50 values are 0.043, > 100 and > 100 μM for GluN1A/2B (NR1A/2B), GluN1A/2A (NR1A/2A) and GluN1A/2C (NR1A/2C) subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Chemical Identifiers

193356-17-1
377.909
co 101244 hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl piperidin-4-ol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol mono hydrochloride, d08nrh, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol monohydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-hydroxy-4-4-methylbenzyl piperidine hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4hydroxy-4-4-methylbenzyl piperidine hydrochloride
1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol;hydrochloride
C21H28ClNO3
WFFZHKKSIDENAJ-UHFFFAOYSA-N
6918426
CC1=CC=C(C=C1)CC2(CCN(CC2)CCOC3=CC=C(C=C3)O)O.Cl

Specifications

Co 101244 hydrochloride
193356-17-1
co 101244 hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl piperidin-4-ol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol mono hydrochloride, d08nrh, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol monohydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-hydroxy-4-4-methylbenzyl piperidine hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4hydroxy-4-4-methylbenzyl piperidine hydrochloride
CC1=CC=C(C=C1)CC2(CCN(CC2)CCOC3=CC=C(C=C3)O)O.Cl
377.909
377.91
50mg
C21H28ClNO3
WFFZHKKSIDENAJ-UHFFFAOYSA-N
1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol;hydrochloride
6918426
>99%
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