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Ch 55, Tocris Bioscience™

Potent RAR agonist

Brand:  Tocris (Bio-Techne) 202010

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13459373

  • £146.00 / 10mg


Estimated Shipment
31-08-2018
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Description

Description

Highly potent synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM).
Specifications

Chemical Identifiers

110368-33-7
364.485
4-[(1E)-3-[3, 5-bis(1, 1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid
C24H28O3
FOUVTBKPJRMLPE-FMIVXFBMSA-N
6184667

Specifications

Ch 55
>98%
4-[(1E)-3-[3, 5-bis(1, 1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid
CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C
364.485
10mg
110368-33-7
C24H28O3
FOUVTBKPJRMLPE-FMIVXFBMSA-N
4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid
6184667
364.47
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