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Ch 55, Tocris Bioscience™

Potent RAR agonist

Brand:  Tocris (Bio-Techne) 202010

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13459373

  • £147.15 / 10mg


Estimated Shipment
29-11-2018
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Description

Description

Highly potent synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM).
Specifications

Chemical Identifiers

110368-33-7
364.485
3,5-di-tert-butylchalcone, 4-1e-3-3,5-di-tert-butylphenyl-3-oxoprop-1-en-1-yl benzoic acid, 4-3-3,5-di-t-butylphenyl-3-oxo-1-propenyl benzoic acid, e-4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl benzoic acid, benzoic acid, 4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl-, e, 3,5-di-tert-butylchalcone-4'-carboxylic acid, e-4-3,5-di-t-butylphenyl-3-oxopropenyl benzoic acid, 4-3-3,5-di-tert-butylphenyl-3-oxo-1-propenyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxo-prop-1-enyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxoprop-1-enyl benzoic acid
4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid
C24H28O3
FOUVTBKPJRMLPE-FMIVXFBMSA-N
6184667
CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C

Specifications

Ch 55
110368-33-7
3,5-di-tert-butylchalcone, 4-1e-3-3,5-di-tert-butylphenyl-3-oxoprop-1-en-1-yl benzoic acid, 4-3-3,5-di-t-butylphenyl-3-oxo-1-propenyl benzoic acid, e-4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl benzoic acid, benzoic acid, 4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl-, e, 3,5-di-tert-butylchalcone-4'-carboxylic acid, e-4-3,5-di-t-butylphenyl-3-oxopropenyl benzoic acid, 4-3-3,5-di-tert-butylphenyl-3-oxo-1-propenyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxo-prop-1-enyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxoprop-1-enyl benzoic acid
CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C
364.485
364.47
10mg
C24H28O3
FOUVTBKPJRMLPE-FMIVXFBMSA-N
4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid
6184667
>98%
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