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CGP 57380, Tocris Bioscience™

Selective inhibitor of Mnk1

Brand:  Tocris (Bio-Techne) 273110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13461824

  • £186.00 / 10mg


Estimated Shipment
02-07-2018
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Description

Description

Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC50 = 2.2 μM) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC50 = 3 μM) and inhibits LPS-induced TNFα expression in macrophages.
Specifications

Chemical Identifiers

CGP 57380
C11H9FN6
244.23
N3-(4-Fluorophenyl)-1H-pyrazolo-[3, 4-d]pyrimidine-3, 4-diamine

Specifications

CGP 57380
522629-08-9
C11H9FN6
N3-(4-Fluorophenyl)-1H-pyrazolo-[3, 4-d]pyrimidine-3, 4-diamine
10mg
>98%
244.23
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