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CGP 55845 hydrochloride, Tocris Bioscience™

Potent and selective GABAB antagonist

Brand:  Tocris (Bio-Techne) 1248/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13428973

  • £202.86 / 10mg

Estimated Shipment date
from Supplier 31-03-2020

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Description

Description

Potent, selective GABAB receptor antagonist (IC50 = 5 nM) that prevents agonist binding (pKi = 8.35) and inhibits GABA and glutamate release (pEC50 values are 8.08 and 7.85 respectively). Inhibits GABAB responses to baclofen (IC50 = 130 nM in an isoproterenol assay) and potentiates the hypoglycemic response to glucose in vitro.
Specifications

Chemical Identifiers

149184-22-5
438.71
cgp 55845 hydrochloride, c18h22cl2no3p.hcl, cgp 55845a hydrochloride, s-r*,r*-isomer, 3-1-s-3,4-dichlorophenyl-ethyl amino 2-s-hydroxypropyl-phenylmethyl-phosphinic acid hydrochloride, phosphinic acid, 2s-3-1s-1-3,4-dichlorophenyl ethyl amino-2-hydroxypropyl phenylmethyl-, hydrochloride
benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid;hydrochloride
C18H23Cl3NO3P
PXQAIXBYWZBYKJ-LINSIKMZSA-N
9954841
CC(C1=CC(=C(C=C1)Cl)Cl)NCC(CP(=O)(CC2=CC=CC=C2)O)O.Cl

Specifications

10mg
149184-22-5
cgp 55845 hydrochloride, c18h22cl2no3p.hcl, cgp 55845a hydrochloride, s-r*,r*-isomer, 3-1-s-3,4-dichlorophenyl-ethyl amino 2-s-hydroxypropyl-phenylmethyl-phosphinic acid hydrochloride, phosphinic acid, 2s-3-1s-1-3,4-dichlorophenyl ethyl amino-2-hydroxypropyl phenylmethyl-, hydrochloride
CC(C1=CC(=C(C=C1)Cl)Cl)NCC(CP(=O)(CC2=CC=CC=C2)O)O.Cl
438.71
438.71
CGP 55845 hydrochloride
C18H23Cl3NO3P
PXQAIXBYWZBYKJ-LINSIKMZSA-N
benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid;hydrochloride
9954841
>98%
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