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CGK 733, Tocris Bioscience™

Induces apoptosis in prematurely senescent cells

Brand:  Tocris (Bio-Techne) 263910

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13461624

  • £146.00 / 10mg


Estimated Shipment
31-08-2018
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Description

Description

Originally defined as a selective inhibitor of ATR and ATM kinases. Induces cell death in prematurely senescent breast cancer cells. Decreases p21CIP1 levels in premature senescent MCF-7 and HCT-116 cells; also exhibits antiproliferative activity in a range of cancer cell lines. Blocks camptothecin-induced p53 phosphorylation and protects cells from camptothecin-induced apoptosis.
Specifications

Chemical Identifiers

905973-89-9
555.83
α-Phenyl-N-[2, 2, 2-trichloro-1-[[[(4-fluoro-3-nitrophenyl)amino]thioxomethyl]amino]ethyl]benzeneacetamide
C23H18Cl3FN4O3S
HLCDNLNLQNYZTK-UHFFFAOYSA-N
6605258

Specifications

CGK 733
905973-89-9
C23H18Cl3FN4O3S
HLCDNLNLQNYZTK-UHFFFAOYSA-N
2,2-diphenyl-N-[2,2,2-trichloro-1-[(4-fluoro-3-nitrophenyl)carbamothioylamino]ethyl]acetamide
6605258
10mg
>98%
α-Phenyl-N-[2, 2, 2-trichloro-1-[[[(4-fluoro-3-nitrophenyl)amino]thioxomethyl]amino]ethyl]benzeneacetamide
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC3=CC(=C(C=C3)F)[N+](=O)[O-]
555.83
555.84
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