CD95 (APO-1/Fas) Mouse anti-Mouse, Clone: 15A7, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0951-85

Product Code. 15217127

Disclaimers:

For Research Use Only.

Description

The 15A7 monoclonal antibody reacts with mouse CD95 (Fas, Apo-1), a 40-50kDa member of the TNFR superfamily. CD95 is expressed by a broad range of hematopoietic and non-hematopoietic cells including monocytes, neutrophils, activated lymphocytes and fibroblasts. Interaction of CD95 on mature lymphocytes with its ligand (FasL) induces apoptosis and is thought to be important in peripheral tolerance. 15A7 reacts with mouse CD95 in BALB/c strain and a bit more weakly in C57Bl/6 strain. 15A7 does not induce apoptosis of Fas-expressing cells.

Specifications

• Antigen: CD95 (APO-1/Fas)
• Clone: 15A7
• Conjugate: Unlabeled
• Format: Purified
• Isotype: IgG1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine

• Applications: Flow Cytometry
• Concentration: 0.5mg/mL
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Murine
• Quantity: 500μg
• Storage Requirements: Store at 2-8°C.
• Monoclonal or Polyclonal: Monoclonal