CD95 (APO-1/Fas) Mouse anti-Mouse, Clone: 15A7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0951-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15217127

Quantity Price
1 £ 146.13 / 500µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Host Species Mouse
Isotype IgG1
Clone 15A7
Primary or Secondary Primary
Species Reactivity Mouse
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Concentration 0.5mg/mL
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry
Quantity 500μg
Antigen CD95 (APO-1/Fas)
Storage Requirements Store at 2-8°C.
Format Purified

The 15A7 monoclonal antibody reacts with mouse CD95 (Fas, Apo-1), a 40-50kDa member of the TNFR superfamily. CD95 is expressed by a broad range of hematopoietic and non-hematopoietic cells including monocytes, neutrophils, activated lymphocytes and fibroblasts. Interaction of CD95 on mature lymphocytes with its ligand (FasL) induces apoptosis and is thought to be important in peripheral tolerance. 15A7 reacts with mouse CD95 in BALB/c strain and a bit more weakly in C57Bl/6 strain. 15A7 does not induce apoptosis of Fas-expressing cells.