CD95 (APO-1/Fas) Mouse anti-Mouse, Alexa Fluor 488, Clone: 15A7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-0951-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15322000

Quantity Price
1 £ 155.16 / 100µg
EU Stock 1
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Description and Specification

Specification

Antigen CD95 (APO-1/Fas)
Species Reactivity Mouse
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Applications Flow Cytometry
Host Species Mouse
Isotype IgG1
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Conjugate Alexa Fluor 488
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Quantity 100μg
Concentration 0.5mg/mL
Clone 15A7

The 15A7 monoclonal antibody reacts with mouse CD95 (Fas, Apo-1), a 40-50kDa member of the TNFR superfamily. CD95 is expressed by a broad range of hematopoietic and non-hematopoietic cells including monocytes, neutrophils, activated lymphocytes and fibroblasts. Interaction of CD95 on mature lymphocytes with its ligand (FasL) induces apoptosis and is thought to be important in peripheral tolerance. 15A7 reacts with mouse CD95 in BALB/c strain and a bit more weakly in C57Bl/6 strain. 15A7 does not induce apoptosis of Fas-expressing cells.