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CD95 (APO-1/Fas) Mouse anti-Canine, Human, APC, Clone: DX2, eBioscience™

Mouse Monoclonal Antibody

£97.75 - £216.00

Specifications

Antigen CD95 (APO-1/Fas)
Clone DX2
Target Species Canine, Human
Conjugate APC
Isotype IgG1, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15577976 View Documents Affymetrix eBioscience
17-0959-42
100 Tests £216.00
100 tests View alternative products
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15567976 View Documents Affymetrix eBioscience
17-0959-41
25 Tests £97.75
25 tests View alternative products
Save Up to 
»
In stock, ready to ship: 3 Please to purchase this item. Need a web account? Register with us today!
Description

Description

CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses.
Specifications

Specifications

CD95 (APO-1/Fas)
Canine, Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
DX2
APC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.