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CD91, PE, clone: A2MR-a2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0919-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15546836

  • £80.50 / 25 tests


Estimated Shipment date
from Supplier 03-07-2018
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Description

Description

Description: The A2MR-a2 monoclonal antibody reacts with human CD91, also known as LRP-1 and alpha-2 macroglobulin receptor. CD91 is a 600 kDa, type 1 transmembrane protein consisting of an alpha and beta chain. The alpha chain interacts with multiple structurally and functionally diverse ligands and the beta chain contains 2 tyrosine phosphorylation motifs capable of interacting with adaptor and signaling proteins. Binding of ligands mediates ligand endocytosis and trafficking to lysosomes. This receptor is expressed by cells in the monocytic lineage, dendritic cells, hepatocytes, firbroblasts, adipocytes, neurons, and syncytiotrophoblast. CD91 is involved in cross-presenting antigens via MHC class I molecules on antigen presenting cells after endocytosis of heat shock protein-peptide complexes. It also plays a role in cell migration and is involved in activating signaling cascades.Applications Reported: This A2MR-a2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This A2MR-a2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD91
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q07954
A2MR, APOER, APR, CD91, FLJ16451, IGFBP3R, LRP, MGC88725, TGFBR5
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
A2MR-a2
PE
LRP1
Conjugated
LRP1
IgG1, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
4035
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