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CD9 Rat anti-Mouse, Clone: eBioKMC8 (KMC8), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0091-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15266787

  • £36.08 / 50µg


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Disclaimers:

For Research Use Only.


Description

Description

The eBioKMC8 monoclonal antibody reacts with mouse CD9, a 24kDa member of the transmembrane 4 superfamily. This family is characterized by the presence of four hydrophobic domains spanning the cell membrane and short N- and C-terminal cytoplasmic domains. CD9 is expressed by several cell types including monocytes, macrophages, platelets, early B cells, activated B and T cells, dendritic cells, eosinophils, basophils, endothelial cells, myoblasts and neuroblasts. On T cells, CD9 functions as a co-stimulatory molecule on naïve T cells. Furthermore, CD9 is expressed in oocytes, and CD9-deficiency results in sterility caused by defective gamete fusion. In mouse macrophages, CD9 functionally associates with FcγRs to modify signals for phagocytosis and inflammatory responses. In mouse B cells, it was discovered that CD9 is a marker for marginal zone B cells, B1 cells, and plasma cells. In dendritic cells, recently it was demonstrated that CD9 facilitates the association of heterologous MHC II molecules. The level of CD9 expression is subject to donor variability.
Specifications

Specifications

CD9
eBioKMC8 (KMC8)
Unlabeled
Purified
Rat
50μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
MIC3, Tspan29
IgG2a
RUO
Primary
Murine