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CD8b Mouse anti-Rat, FITC, Clone: eBio341 (341), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0080-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15258009

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Specifications

Description

The eBio341 monoclonal antibody reacts with rat CD8β. CD8β is a member of the immunoglobulin superfamily which heterodimerizes with CD8α to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class I-restricted peripheral T cells, and on some macrophages. CD8β expression is absent in athymic mice, which are populated by T-cells expressing CD8α homodimers. This has led to the idea that CD8β expression is dependent on the development of T cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates in T-cell receptor signal transduction through association with the kinase Lck.
Description & Specifications

Specifications

CD8b
eBio341 (341)
FITC
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
500μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.5mg/mL
Conjugated
CD8 beta, Ly-3
IgG1
RUO
Primary
Rat