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CD8b Mouse anti-Rat, FITC, Clone: eBio341 (341), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0080-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15248009

  • £54.42 / 50µg


Estimated Shipment date
from Supplier 25-09-2017
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Disclaimers:

For Research Use Only.


Description

Description

The eBio341 monoclonal antibody reacts with rat CD8β. CD8β is a member of the immunoglobulin superfamily which heterodimerizes with CD8α to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class I-restricted peripheral T cells, and on some macrophages. CD8β expression is absent in athymic mice, which are populated by T-cells expressing CD8α homodimers. This has led to the idea that CD8β expression is dependent on the development of T cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates in T-cell receptor signal transduction through association with the kinase Lck.
Specifications

Specifications

CD8b
eBio341 (341)
FITC
Conjugated
Murine
50μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CD8 beta, Ly-3
IgG1
RUO
Primary
Rat