CD8b Mouse anti-Human, Non-human primate, eFluor 660, Clone: SIDI8BEE, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-5273-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15599966

Quantity Price
1 £ 66.65 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Quantity 25 Tests
Host Species Murine
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human, Non-human primate
Clone SIDI8BEE
Applications Flow Cytometry
Concentration 5μL (0.125μg)/test
Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate eFluor 660
Antigen CD8b

The SIDI8BEE monoclonal antibody reacts with human and rhesus macaque CD8 beta. The CD8b chain associates with the CD8a chain to form the CD8ab heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alphabeta TCR T cells. The CD8 receptor complex binds to MHC class I and plays a role in T cell development and activation of mature T cells. Long been thought to exist either as a heterodimer of the alpha and beta chain or as a homodimer of alpha chains, beta chains have now been shown to homodimerize as well. SIDI8BEE can detect the CD8 beta chain in both the CD8ab heterodimer and the CD8bb homodimer.

SIDI8BEE is cross-reactive to human and rhesus macaque CD8b. Other non-human primate species have not been tested.