CD8b Mouse anti-Human, Non-human primate, eFluor 660, Clone: SIDI8BEE, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-5273-42

100TEST Anti-Human/Non-Human Primate CD8b eFluor 660

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15509976

Quantity Price
1 £ 250.6 / 100 tests
Estimated Shipment date
from Supplier 07-12-2016
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Description and Specification

Specification

Antigen CD8b
Applications Flow Cytometry
Clone SIDI8BEE
Concentration 5μL (0.125μg)/test
Conjugate eFluor 660
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Isotype IgG1
Quantity 100 tests
Regulatory Status RUO
Species Reactivity Human, Non-human primate
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The SIDI8BEE monoclonal antibody reacts with human and rhesus macaque CD8 beta. The CD8b chain associates with the CD8a chain to form the CD8ab heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alphabeta TCR T cells. The CD8 receptor complex binds to MHC class I and plays a role in T cell development and activation of mature T cells. Long been thought to exist either as a heterodimer of the alpha and beta chain or as a homodimer of alpha chains, beta chains have now been shown to homodimerize as well. SIDI8BEE can detect the CD8 beta chain in both the CD8ab heterodimer and the CD8bb homodimer.

SIDI8BEE is cross-reactive to human and rhesus macaque CD8b. Other non-human primate species have not been tested.