CD8a, PE-Cyanine5, clone: 53-6.7, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 15-0081-82
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionThe 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|CD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2|
For Research Use Only.