CD8a Rat anti-Mouse, PE, Clone: 53-6.7, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0081-83

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15288439

Quantity Price
1 £ 91.11 / 200µg
EU Stock 7
Add to basket


Description and Specification

Specification

Antigen CD8a
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Conjugate PE
Host Species Rat
Regulatory Status RUO
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Isotype IgG2a
Quantity 200μg
Clone 53-6.7
Species Reactivity Mouse
Gene Alias CD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2
Concentration 0.2mg/mL
Applications Flow Cytometry

The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.