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CD8a Rat anti-Mouse, Biotin, Clone: 53-6.7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0081-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15269429

  • £29.97 / 50µg


Estimated Shipment date
from Supplier 29-06-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.
Description & Specifications

Specifications

CD8a
53-6.7
Biotin
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
50μg
Store at 2-8°C. Do not freeze.
Monoclonal
Immunohistochemistry (Frozen)
0.5mg/mL
Conjugated
CD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2
IgG2a
RUO
Primary
Murine