missing translation for 'onlineSavingsMsg'
Learn More

CD8a, Biotin, clone: 53-6.7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0081-86

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15299429

  • £242.09 / 1mg


Estimated Shipment date
from Supplier 25-07-2018
Add to basket

Description

Description

Description: The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.Applications Reported: The 53-6.7 antibody has been reported for use in flow cytometric analysis and immunohistochemistry.Applications Tested: The 53-6.7 antibody has been tested by flow cytometric analysis of mouse thymocytes and splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD8a
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P01731
CD8, Leu-2, MAL, p32, CD8a
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow CytometryĆ¾Immunohistochemistry (Frozen)
53-6.7
Biotin
Cd8a
Conjugated
Cd8a
IgG2a, kappa
1mg
Store at 2-8°C. Do not freeze.
Primary
12525
Videos

For Research Use Only.