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CD8a Mouse anti-Human, PE-Cyanine5.5, Clone: RPA-T8, eBioscience™

Mouse Monoclonal Antibody

£78.00 - £194.00

Specifications

Antigen CD8a
Clone RPA-T8
Target Species Human
Conjugate PE-Cyanine5.5
Isotype IgG1, kappa
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15578846
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Affymetrix eBioscience
35-0088-41
25 Tests £78.00
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Estimated Shipment
23-11-2020
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15588846
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Affymetrix eBioscience
35-0088-42
100 Tests £194.00
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Description

Description

Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488-561 nm; Emission: 690 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).
Specifications

Specifications

CD8a
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
RPA-T8
PE-Cyanine5.5
Flow Cytometry
Primary
Monoclonal
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.