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CD8a Mouse anti-Human, PE, Clone: SK1, eBioscience™
Mouse Monoclonal Antibody
£93.50 - £219.00
Specifications
Antigen | CD8a |
---|---|
Clone | SK1 |
Target Species | Human |
Conjugate | PE |
Isotype | IgG1, kappa |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15576696
|
Affymetrix eBioscience
12-0087-41 |
25 Tests |
£93.50
25 tests |
Estimated Shipment 26-02-2021 |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
15586696
|
Affymetrix eBioscience
12-0087-42 |
100 Tests |
£219.00
100 tests |
In stock, ready to ship: 3 | Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).Specifications
CD8a | |
Human | |
IgG1, kappa | |
Monoclonal | |
Liquid | |
Antibody | |
4° C, store in dark, DO NOT FREEZE! |
SK1 | |
PE | |
Flow Cytometry | |
Primary | |
Monoclonal | |
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
RUO |
For Research Use Only.