CD8a Mouse anti-Human, eFluor 450, Clone: RPA-T8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0088-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15589626

Quantity Price
1 £ 72.77 / 25 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Primary or Secondary Primary
Host Species Mouse
Quantity 25 tests
Regulatory Status RUO
Conjugate eFluor 450
Clone RPA-T8
Concentration 5μL (0.25μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Isotype IgG1
Gene Alias CD8 alpha, leu-2a
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD8a

The RPA-T8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells.