CD8a Mouse anti-Human, Clone: C8/144B, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0085-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15206787

Quantity Price
1 £ 66.65 / 100µg
EU Stock 2
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Description and Specification

Specification

Species Reactivity Human
Isotype IgG1
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Gene Alias Leu-2a
Clone C8/144B
Primary or Secondary Primary
Host Species Mouse
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 100μg
Format Purified
Antigen CD8a
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL

The monoclonal antibody C8/144B recognizes the human CD8a molecule, an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.