CD8a, clone: AMC908, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-0008-80
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: This AMC908 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alphaalpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells.Applications Reported: This AMC908 antibody has been reported for use in western blotting, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This AMC908 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using high pH antigen retrieval. This can be used at less than or equal to 0.5 μg/mL. This AMC908 antibody has been tested by western blot of reduced peripheral blood mononuclear cells and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.09% sodium azide; pH 7.2|
|CD8, Leu-2, MAL, p32, CD8a|
|Immunohistochemistry (Paraffin), Western Blot|
|IgG2a, kappa, kappa|
|Store at 2-8°C.|
For Research Use Only.