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CD86 (B7-2) Mouse anti-Rat, FITC, Clone: 24F, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0860-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15278139

  • £103.33 / 100µg


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Disclaimers:

For Research Use Only.


Description

Description

The 24F monoclonal antibody reacts with rat CD86, an ∽90kDa surface receptor, also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed by germinal center B cells and at low levels on macrophages, dendritic cells and non-lymphoid cells in the thymus. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
Specifications

Specifications

CD86
24F
FITC
Conjugated
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
B72
IgG1
RUO
Primary
Rat
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