missing translation for 'onlineSavingsMsg'
Learn More

CD86 (B7-2) Mouse anti-Rat, FITC, Clone: 24F, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0860-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15278139

  • £103.33 / 100µg


Estimated Shipment date
from Supplier 30-08-2017
Add to basket

Disclaimers:

For Research Use Only.


Specifications

Description

The 24F monoclonal antibody reacts with rat CD86, an ∽90kDa surface receptor, also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed by germinal center B cells and at low levels on macrophages, dendritic cells and non-lymphoid cells in the thymus. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
Description & Specifications

Specifications

CD86 (B7-2)
24F
FITC
Conjugated
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
B72
IgG1
RUO
Primary
Rat