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CD86 (B7-2) Mouse anti-Human, PerCP-eFluor 710, Clone: IT2.2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-0869-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15559156

  • £108.75 / 25 tests


EU Stock 4
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Disclaimers:

For Research Use Only.


Description

Description

The IT2.2 monoclonal antibody reacts with human CD86, an ∽80kDa surface receptor also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low levels on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
Specifications

Specifications

CD86 (B7-2)
IT2.2
PerCP-eFluor™ 710
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
B72, B70
IgG2b
RUO
Primary
Human