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CD85k (ILT3) Mouse anti-Human, Clone: ZM4.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-5139-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15258637

  • £225.61 / 500µg


EU Stock 2
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.
Description & Specifications

Specifications

CD85k (ILT3)
ZM4.1
Unlabeled
aqueous buffer, no sodium azide
Murine
500μg
Store at 2-8°C.
Monoclonal
Functional Assay
1mg/mL
Purified
ILT-3, LIR5, LILRB4, HM18, GM 4d
IgG1
RUO
Primary
Human