CD85k (ILT3) Mouse anti-Human, Clone: ZM4.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-5139-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15258637

Quantity Price
1 £ 225.61 / 500µg
EU Stock 2
Add to basket


Description and Specification

Specification

Host Species Murine
Storage Requirements Store at 2-8°C.
Concentration 1mg/mL
Regulatory Status RUO
Quantity 500μg
Primary or Secondary Primary
Antigen CD85k (ILT3)
Applications Flow Cytometry
Applications Functional Assay
Formulation aqueous buffer, no sodium azide
Isotype IgG1
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Gene Alias ILT-3, LIR5, LILRB4, HM18, GM 4d
Format Purified
Clone ZM4.1
Species Reactivity Human

The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.