CD85k (ILT3) Mouse anti-Human, Clone: ZM4.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-5139-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15248637

Quantity Price
1 £ 66.65 / 50µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Species Reactivity Human
Concentration 1mg/mL
Gene Alias ILT-3, LIR5, LILRB4, HM18, GM 4d
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Host Species Mouse
Quantity 50μg
Format Purified
Formulation aqueous buffer, no sodium azide
Clone ZM4.1
Regulatory Status RUO
Applications Flow Cytometry
Applications Functional Assay
Primary or Secondary Primary
Conjugate Unlabeled
Antigen CD85k (ILT3)

The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.