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CD85k (ILT3) Mouse anti-Human, APC, Clone: ZM4.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-5139-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15518116

  • £91.11 / 25 tests


Estimated Shipment date
from Supplier 30-10-2017
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Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.
Specifications

Specifications

CD85k (ILT3)
ZM4.1
APC
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
LIR5, LILRB4, HM18, GM 4d
IgG1
RUO
Primary
Human