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CD85g (ILT7) Mouse anti-Human, APC, Clone: 17G10.2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-5179-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15568116

  • £152.25 / 100 tests


Estimated Shipment date
from Supplier 30-06-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The eBio17G10.2 monoclonal antibody reacts with human immunoglobulin-like transcript 7 (ILT7), also known as CD85g. ILT7 is part of the leukocyte immunoglobulin-like receptor (LIR) gene family and associates with FcεR1γ to form a functional complex which transduces ITAM-mediated signals that negatively modulates TLR-induced type I IFN production by human plasmacytoid dendritic cells. ILT7 is expressed exclusively on plasmacytoid dendritic cells and is absent in monocyte derived DCs. Treatment with IL-3 or CpG causes a decrease in expression.

Double staining of human PBMCs with eBio17G10.2 and anti-pDC marker BDCA2 yields virtually complete co-staining. Cross linking of ILT7 with eBio17G10.2 antibody causes reduced transcription of IFN-α1, IFN-α2, IFN-α4 and IFN-β.
Description & Specifications

Specifications

CD85g (ILT7)
eBio17G10.2 (17G10.2)
Allophycocyanin
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
IgG1
RUO
Primary
Human
Flow Cytometry
5μL (0.25μg)/test
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal