CD81 Mouse anti-Human, PerCP-eFluor 710, Clone: 1D6-CD81, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-0819-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15529156

Quantity Price
1 £ 94.28 / 25 tests
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25 tests
Gene Alias TAPA-1
Primary or Secondary Primary
Clone 1D6-CD81
Host Species Mouse
Regulatory Status RUO
Concentration 5μL (0.5μg)/test
Isotype IgG1
Format Conjugated
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate PerCP-eFluor 710
Species Reactivity Human
Antigen CD81
Monoclonal or Polyclonal Monoclonal

This 1D6-CD81 monoclonal antibody reacts with human CD81, which is also known as Target of Anti-Proliferative Ab-1 (TAPA-1). A member of the tetraspanin superfamily of transmembrane proteins, CD81 is widely expressed on immune cells such as B, T, and NK cells, monocytes, and eosinophils. Studies suggest that the highest expression of CD81 can be found on germinal center B cells. This protein can also be detected on non-Hodgkin lymphomas and diffuse large B-cell lymphomas. On B cells, CD81 exists in a complex with CD19, CD21, and Leu13. CD81 plays a role in segregating the CD19/CD21-B cell receptor complexes to lipid rafts to activate signal transduction. Finally, CD81 is a receptor for hepatitis C virus.

The 1D6 monoclonal antibody has been reported to induce adhesion and reduce cell proliferation.