CD81 Mouse anti-Human, PerCP-eFluor 710, Clone: 1D6-CD81, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-0819-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15539156

Quantity Price
1 £ 195.53 / 100 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Isotype IgG1
Applications Flow Cytometry
Format Conjugated
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100 tests
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.5μg)/test
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Species Reactivity Human
Host Species Mouse
Clone 1D6-CD81
Conjugate PerCP-eFluor 710
Gene Alias TAPA-1
Antigen CD81

This 1D6-CD81 monoclonal antibody reacts with human CD81, which is also known as Target of Anti-Proliferative Ab-1 (TAPA-1). A member of the tetraspanin superfamily of transmembrane proteins, CD81 is widely expressed on immune cells such as B, T, and NK cells, monocytes, and eosinophils. Studies suggest that the highest expression of CD81 can be found on germinal center B cells. This protein can also be detected on non-Hodgkin lymphomas and diffuse large B-cell lymphomas. On B cells, CD81 exists in a complex with CD19, CD21, and Leu13. CD81 plays a role in segregating the CD19/CD21-B cell receptor complexes to lipid rafts to activate signal transduction. Finally, CD81 is a receptor for hepatitis C virus.

The 1D6 monoclonal antibody has been reported to induce adhesion and reduce cell proliferation.