CD80 (B7-1) Mouse anti-Human, PE-Cy5, Clone: 2D10.4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 15-0809-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15587736

Quantity Price
1 £ 174.09 / 100 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human
Clone 2D10.4
Applications Flow Cytometry
Quantity 100 tests
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Regulatory Status RUO
Conjugate PE-Cy5
Concentration 5μL (1μg)/test
Antigen CD80 (B7-1)
Host Species Mouse
Gene Alias B71, BB1
Primary or Secondary Primary
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The 2D10.4 monoclonal antibody reacts with human CD80 (B7-1), a 60kDa member of the Ig superfamily. CD80 is expressed by activated B cells, macrophages and dendritic cells. In addition, activated T cells express this antigen. CD80 has high affinity for binding to two T cell surface antigens, CD28 and CD152 (CTLA-4). The interaction of CD28 and CD152 with CD80 is crucial in T-B cell communication leading to activation of T and B cells, respectively.