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CD80 (B7-1) Mouse anti-Human, PE-Cyanine5, Clone: 2D10.4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 15-0809-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15577736

  • £87.00 / 25 tests

Estimated Shipment date
from Supplier 24-03-2020

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Description

Description

Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488-561 nm; Emission: 667 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Specifications

Specifications

CD80 (B7-1)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P33681
B7-1, B7.1, Cd28l, Ly-53, Ly53, MIC17, TS/A-1, LAB7, B7.1, CD28LG, CD28LG1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
2D10.4
PE-Cyanine5
CD80
Liquid
CD80
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
941
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