CD80 (B7-1) Mouse anti-Human, Clone: 2D10.4, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0809-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15218517

Quantity Price
1 £ 195.05 / 500µg
Estimated Shipment date
from Supplier 06-06-2017
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Description and Specification

Specification

Antigen CD80 (B7-1)
Applications Flow Cytometry
Applications Functional Assay
Clone 2D10.4
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias B71, BB1
Host Species Murine
Isotype IgG1
Quantity 500μg
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

The 2D10.4 monoclonal antibody reacts with human CD80 (B7-1), a 60kDa member of the Ig superfamily. CD80 is expressed by activated B cells, macrophages and dendritic cells. In addition, activated T cells express this antigen. CD80 has high affinity for binding to two T cell surface antigens, CD28 and CD152 (CTLA-4). The interaction of CD28 and CD152 with CD80 is crucial in T-B cell communication leading to activation of T and B cells, respectively.