CD80 (B7-1) Armenian Hamster anti-Canine, Mouse, Porcine, PerCP-eFluor™ 710, Clone: 16-10A1, eBioscience™
Armenian Hamster Monoclonal Antibody
Brand: Affymetrix eBioscience 46-0801-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionPlease protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|B7-1, B7.1, Cd28l, Ly-53, Ly53, MIC17, TS/A-1, LAB7, B7.1, CD28LG, CD28LG1|
|Canine, Mouse, Porcine|
|4° C, store in dark, DO NOT FREEZE!|
|12519, 397161, 403765|
For Research Use Only.