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CD8 Mouse anti-Human, Clone: OKT8 (OKT-8), Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-0086-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15278367

  • £66.65 / 50µg


Estimated Shipment
07-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The OKT8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 αβ) or as a homodimer (CD8 αα). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells. Preliminary testing indicates that OKT8 and two other mouse anti-human CD8 antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat. No.14-0089) do not compete with each other for binding to human peripheral blood leukocytes by flow cytometric analysis, suggesting that they do not bind to similar epitopes or block each other by steric hindrance.
Description & Specifications

Specifications

CD8
OKT8 (OKT-8)
Purified
CD8 alpha, leu-2a
IgG2a
RUO
Primary
Human
Flow Cytometry
Unlabeled
aqueous buffer, no sodium azide
Murine
50μg
Store at 2-8°C.
Monoclonal