missing translation for 'onlineSavingsMsg'
Learn More

CD8a, Biotin, clone: OKT8 (OKT-8), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0086-82

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15219439

  • £111.83 / 100µg


Estimated Shipment date
from Supplier 26-06-2018
Add to basket

Description

Description

Description: The OKT8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alphaalpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells. Preliminary testing indicates that OKT8 and two other mouse anti-human CD8 antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat. No.14-0089) do not compete with each other for binding to human peripheral blood leukocytes by flow cytometric analysis, suggesting that they do not bind to similar epitopes or block each other by steric hindrance.Applications Reported: This OKT8 (OKT-8) antibody has been reported for use in flow cytometric analysis.Applications Tested: This OKT8 (OKT-8) antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.06 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD8
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P01732
CD8, Leu-2, MAL, p32, CD8a
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
OKT8 (OKT-8)
Biotin
CD8A
Conjugated
CD8A
IgG2a
100μg
Store at 2-8°C. Do not freeze.
Primary
925
Videos

For Research Use Only.