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CD8a Mouse anti-Human, Alexa Fluor® 700, Clone: OKT8 (OKT-8), eBioscience™
Mouse Monoclonal Antibody
£71.75 - £187.00
Specifications
Antigen | CD8a |
---|---|
Clone | OKT8 (OKT-8) |
Target Species | Human |
Conjugate | Alexa Fluor™ 700 |
Isotype | IgG2a, kappa |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15590327
|
Affymetrix eBioscience
56-0086-42 |
100 Tests |
£187.00
100 tests |
In stock, ready to ship: 1 | Please sign in to purchase this item. Need a web account? Register with us today! | ||||
15580327
|
Affymetrix eBioscience
56-0086-41 |
25 Tests |
£71.75
25 tests |
Estimated Shipment 26-01-2021 |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Alexa Fluor™ 700 emits at 723 nm and can be excited with the red laser (633 nm). Most instruments will require a 685 LP mirror and 710/20 filter. Please make sure that your instrument is capable of detecting this fluorochrome. Excitation: 633-647 nm; Emission: 723 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).Specifications
CD8a | |
Human | |
IgG2a, kappa | |
Monoclonal | |
Liquid | |
Antibody | |
4° C, store in dark, DO NOT FREEZE! |
OKT8 (OKT-8) | |
Alexa Fluor™ 700 | |
Flow Cytometry | |
Primary | |
Monoclonal | |
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
RUO |
For Research Use Only.