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CD73 Rat anti-Mouse, PE, Clone: eBioTY/11.8 (TY/11.8), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0731-83

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15288589

  • £198.54 / 200µg


Estimated Shipment date
from Supplier 30-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

eBioTY/11.8 recognizes the with CD73 a 69kDa GPI-anchored cell-surface protein with ecto-5'-nucleotidase activity. Expression on myeloid cells (CD11b) is restricted to the bone marrow. In human CD73 can be induced to secrete a soluble form with IL-2 suggesting a role in mediating activation signals. Differences between human and mouse CD73 have been reported. BALB/c mice have more CD4+CD73+ than CD8+CD73+ while the reciprocal is documented in humans.

CD73 is expressed on a subset of lymphocytes and increases during lymphocyte maturation. Recently it has been found that memory CD4 T cells express and are similar to the uncommitted primed precursor helper cells (Thpp) that can differentiate into Th1 or Th2 cells. Furthermore CD73 has been found on regulatory T cells.
Description & Specifications

Specifications

CD73
eBioTY/11.8 (TY/11.8)
PE
Conjugated
Rat
200μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Ecto-5'-nucleotidase, NT5E
IgG1
RUO
Primary
Murine