CD7, PE, clone: CD7-6B7, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MHCD07044

Product Code. 10672024

Description

CD7 (gp40, Leu9) is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.

Specifications

• Antigen: CD7
• Classification: Monoclonal
• Conjugate: PE
• Gene: CD7
• Gene Alias: GP40, LEU-9, TP41, Tp40
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: ASR, ASR/IVD
• Gene ID (Entrez): 924
• Content And Storage: Store at 2 - 8 °C.
• Form: Liquid

• Applications: Flow Cytometry
• Clone: CD7-6B7
• Formulation: PBS with 4mg/mL BSA, sucrose and 0.1% sodium azide
• Gene Accession No.: P09564
• Gene Symbols: CD7
• Immunogen: Human CD7
• Quantity: 2 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a