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CD7 Mouse anti-Human, FITC, Clone: 4H9, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0078-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15576316

  • £65.75 / 25 tests

Estimated Shipment date
from Supplier 02-04-2020

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Description

Description

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on maligt B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3′-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.
Specifications

Specifications

CD7
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P09564
GP40, LEU-9, TP41, Tp40
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
4H9
FITC
CD7
Liquid
CD7
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
924
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For Research Use Only.