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CD7 Mouse anti-Human, FITC, Clone: 4H9, eBioscience™

Mouse Monoclonal Antibody

£65.75 - £144.00

Specifications

Antigen CD7
Clone 4H9
Target Species Human
Conjugate FITC
Isotype IgG2a, kappa
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15576316
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Affymetrix eBioscience
11-0078-41
25 Tests £65.75
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Estimated Shipment
23-11-2020
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15586316
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Affymetrix eBioscience
11-0078-42
100 Tests £144.00
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Description

Description

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on maligt B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3′-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.
Specifications

Specifications

CD7
Human
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
4H9
FITC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.